Many theories about the cause of schizophrenia involve changes in the activity of a neurotransmitter

Many
theories about the cause of schizophrenia involve changes in the activity of a
neurotransmitter chemical called dopamine in the brain. In a 1982 study,
Sternberg, Van Kammen, Lerner, and Bunney examined 25 hospitalized
schizophrenic patients who were treated with an antipsychotic medication. After
a period of time, these same patients were classified as psychotic and
nonpsychotic by hospital staff. Samples of cerebrospinal fluid (CSF) were taken
from each patient and assayed for dopamine _-hydroxylase (DBH) activity.
DBH is an enzyme used in the brain to break do pa-mine down into its
»

Many
theories about the cause of schizophrenia involve changes in the activity of a
neurotransmitter chemical called dopamine in the brain. In a 1982 study,
Sternberg, Van Kammen, Lerner, and Bunney examined 25 hospitalized
schizophrenic patients who were treated with an antipsychotic medication. After
a period of time, these same patients were classified as psychotic and
nonpsychotic by hospital staff. Samples of cerebrospinal fluid (CSF) were taken
from each patient and assayed for dopamine _-hydroxylase (DBH) activity.
DBH is an enzyme used in the brain to break do pa-mine down into its inactive
component parts. Levels of DBH are used as an indirect measure of dopamine
levels. The more DBH present in the CSF, the more dopamine present in the
brain. The data in Table 6.9 show the average level of DBH in two groups of
schizophrenic patients. Group 1included 15 male patients who were diagnosed
with schizophrenia but did not display psychotic features of the disorder.
Group 2 included 10 male patients who were diagnosed with schizophrenia and did
display psychotic features. The larger the number, the more DBH was present in
the CSF (units of measure are nmol/ml/mg of protein).

 

 

a.
Describe the difference in DBH levels between the two groups. Which group had
the higher mean? Which group had more variability in their DBH levels?

b.
Let’s compare the mean DBH level in Group 2 with the distribution of DBH in the
nonpsychotic group (Group 1). Convert the mean DBH level in Group 2 to a
z-score in the Group 1 distribution.

c.
What does the z-score you just calculated tell you about the possible
relationship between DBH level and psychotic features in schizophrenia?

 

»

Place your order
(550 words)

Approximate price: $22

Calculate the price of your order

550 words
We'll send you the first draft for approval by September 11, 2018 at 10:52 AM
Total price:
$26
The price is based on these factors:
Academic level
Number of pages
Urgency
Basic features
  • Free title page and bibliography
  • Unlimited revisions
  • Plagiarism-free guarantee
  • Money-back guarantee
  • 24/7 support
On-demand options
  • Writer’s samples
  • Part-by-part delivery
  • Overnight delivery
  • Copies of used sources
  • Expert Proofreading
Paper format
  • 275 words per page
  • 12 pt Arial/Times New Roman
  • Double line spacing
  • Any citation style (APA, MLA, Chicago/Turabian, Harvard)

Our guarantees

Delivering a high-quality product at a reasonable price is not enough anymore.
That’s why we have developed 5 beneficial guarantees that will make your experience with our service enjoyable, easy, and safe.

Money-back guarantee

You have to be 100% sure of the quality of your product to give a money-back guarantee. This describes us perfectly. Make sure that this guarantee is totally transparent.

Read more

Zero-plagiarism guarantee

Each paper is composed from scratch, according to your instructions. It is then checked by our plagiarism-detection software. There is no gap where plagiarism could squeeze in.

Read more

Free-revision policy

Thanks to our free revisions, there is no way for you to be unsatisfied. We will work on your paper until you are completely happy with the result.

Read more

Privacy policy

Your email is safe, as we store it according to international data protection rules. Your bank details are secure, as we use only reliable payment systems.

Read more

Fair-cooperation guarantee

By sending us your money, you buy the service we provide. Check out our terms and conditions if you prefer business talks to be laid out in official language.

Read more